Ontology highlight
ABSTRACT:
SUBMITTER: Raghuraman S
PROVIDER: S-EPMC4035978 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Raghuraman Shrinivasan S Garcia Alfredo J AJ Anderson Tatiana M TM Twede Vernon D VD Curtice Kigen J KJ Chase Kevin K Ramirez Jan-Marino JM Olivera Baldomero M BM Teichert Russell W RW
Proceedings of the National Academy of Sciences of the United States of America 20140414 17
Previously we defined neuronal subclasses within the mouse peripheral nervous system using an experimental strategy called "constellation pharmacology." Here we demonstrate the broad applicability of constellation pharmacology by extending it to the CNS and specifically to the ventral respiratory column (VRC) of mouse brainstem, a region containing the neuronal network controlling respiratory rhythm. Analysis of dissociated cells from this locus revealed three major cell classes, each encompassi ...[more]