Individual risk of cutaneous melanoma in New Zealand: developing a clinical prediction aid.

ABSTRACT:

Background

New Zealand and Australia have the highest melanoma incidence rates worldwide. In New Zealand, both the incidence and thickness have been increasing. Clinical decisions require accurate risk prediction but a simple list of genetic, phenotypic and behavioural risk factors is inadequate to estimate individual risk as the risk factors for melanoma have complex interactions. In order to offer tailored clinical management strategies, we developed a New Zealand prediction model to estimate individual 5-year absolute risk of melanoma.

Methods

A population-based case-control study (368 cases and 270 controls) of melanoma risk factors provided estimates of relative risks for fair-skinned New Zealanders aged 20-79 years. Model selection techniques and multivariate logistic

SUBMITTER: Sneyd MJ 

PROVIDER: S-EPMC4038363 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature