Ontology highlight
ABSTRACT:
SUBMITTER: Moor AN
PROVIDER: S-EPMC4039282 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Moor Andrea N AN Tummel Evan E Prather Jamie L JL Jung Michelle M Lopez Jonathan J JJ Connors Sarah S Gould Lisa J LJ
Age (Dordrecht, Netherlands) 20140121 2
Advertisements targeted at the elderly population suggest that antioxidant therapy will reduce free radicals and promote wound healing, yet few scientific studies substantiate these claims. To better understand the potential utility of supplemental antioxidant therapy for wound healing, we tested the hypothesis that age and tissue ischemia alter the balance of endogenous antioxidant enzymes. Using a bipedicled skin flap model, ischemic and non-ischemic wounds were created on young and aged rats. ...[more]