Ontology highlight
ABSTRACT:
SUBMITTER: Negru S
PROVIDER: S-EPMC4039802 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Negru Serban S Papadopoulou Eirini E Apessos Angela A Stanculeanu Dana Lucia DL Ciuleanu Eliade E Volovat Constantin C Croitoru Adina A Kakolyris Stylianos S Aravantinos Gerasimos G Ziras Nikolaos N Athanasiadis Elias E Touroutoglou Nikolaos N Pavlidis Nikolaos N Kalofonos Haralabos P HP Nasioulas George G
BMJ open 20140523 5
<h4>Objectives</h4>Treatment decision-making in colorectal cancer is often guided by tumour tissue molecular analysis. The aim of this study was the development and validation of a high-resolution melting (HRM) method for the detection of KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer and determination of the frequency of these mutations in the respective populations.<h4>Setting</h4>Diagnostic molecular laboratory located in Athens, Greece.<h4>Participants</h ...[more]