Ontology highlight
ABSTRACT:
SUBMITTER: Goede V
PROVIDER: S-EPMC4040914 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Goede Valentin V Cramer Paula P Busch Raymonde R Bergmann Manuela M Stauch Martina M Hopfinger Georg G Stilgenbauer Stephan S Döhner Hartmut H Westermann Anne A Wendtner Clemens M CM Eichhorst Barbara B Hallek Michael M
Haematologica 20140228 6
This study investigated the impact of comorbidity in 555 patients with chronic lymphocytic leukemia enrolled in two trials of the German Chronic Lymphocytic Leukemia Study Group on first-line treatment with fludarabine plus cyclophosphamide, fludarabine, or chlorambucil. Patients with two or more comorbidities and patients with less than two comorbidities differed in overall survival (71.7 versus 90.2 months; P<0.001) and progression-free survival (21.0 versus 31.5 months; P<0.01). After adjustm ...[more]