Ancestral hemoglobins in Archaea.
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ABSTRACT:
SUBMITTER: Freitas TA
PROVIDER: S-EPMC404104 | biostudies-literature | 2004 Apr
REPOSITORIES: biostudies-literature
Publications
Ancestral hemoglobins in Archaea.
Freitas Tracey Allen K TA Hou Shaobin S Dioum Elhadji M EM Saito Jennifer A JA Newhouse James J Gonzalez Gonzalo G Gilles-Gonzalez Marie-Alda MA Alam Maqsudul M
Proceedings of the National Academy of Sciences of the United States of America 20040419 17
Hemoglobins are ubiquitous in Eukarya and Bacteria but, until now, have not been found in Archaea. A phylogenetic analysis of the recently revealed microbial family of globin-coupled heme-based sensors suggests that these sensors descended from an ancient globin-only progenitor, or a protoglobin (Pgb). Here, we report the discovery and characterization of two Pgbs from the Archaea: ApPgb from the obligately aerobic hyperthermophile Aeropyrum pernix, and MaPgb from the strictly anaerobic methanog ...[more]
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