Dataset Information

Advancing bag-of-visual-words representations for lesion classification in retinal images.

ABSTRACT: Diabetic Retinopathy (DR) is a complication of diabetes that can lead to blindness if not readily discovered. Automated screening algorithms have the potential to improve identification of patients who need further medical attention. However, the identification of lesions must be accurate to be useful for clinical application. The bag-of-visual-words (BoVW) algorithm employs a maximum-margin classifier in a flexible framework that is able to detect the most common DR-related lesions such as microaneurysms, cotton-wool spots and hard exudates. BoVW allows to bypass the need for pre- and post-processing of the retinographic images, as well as the need of specific ad hoc techniques for identification of each type of lesion. An extensive evaluation of the BoVW model, using three large retinograph datasets (DR1, DR2 and Messidor) with different resolution and collected by different healthcare personnel, was performed. The results demonstrate that the BoVW classification approach can identify different lesions within an image without having to utilize different algorithms for each lesion reducing processing time and providing a more flexible diagnostic system. Our BoVW scheme is based on sparse low-level feature detection with a Speeded-Up Robust Features (SURF) local descriptor, and mid-level features based on semi-soft coding with max pooling. The best BoVW representation for retinal image classification was an area under the receiver operating characteristic curve (AUC-ROC) of 97.8% (exudates) and 93.5% (red lesions), applying a cross-dataset validation protocol. To assess the accuracy for detecting cases that require referral within one year, the sparse extraction technique associated with semi-soft coding and max pooling obtained an AUC of 94.2 ± 2.0%, outperforming current methods. Those results indicate that, for retinal image classification tasks in clinical practice, BoVW is equal and, in some instances, surpasses results obtained using dense detection (widely believed to be the best choice in many vision problems) for the low-level descriptors.

SUBMITTER: Pires R

PROVIDER: S-EPMC4041723 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Advancing bag-of-visual-words representations for lesion classification in retinal images.

Pires Ramon R Jelinek Herbert F HF Wainer Jacques J Valle Eduardo E Rocha Anderson A

PloS one 20140602 6

Diabetic Retinopathy (DR) is a complication of diabetes that can lead to blindness if not readily discovered. Automated screening algorithms have the potential to improve identification of patients who need further medical attention. However, the identification of lesions must be accurate to be useful for clinical application. The bag-of-visual-words (BoVW) algorithm employs a maximum-margin classifier in a flexible framework that is able to detect the most common DR-related lesions such as micr ...[more]

PMID: 24886780

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Project description:Text classification (TC) is the task of automatically assigning documents to a fixed number of categories. TC is an important component in many text applications. Many of these applications perform preprocessing. There are different types of text preprocessing, e.g., conversion of uppercase letters into lowercase letters, HTML tag removal, stopword removal, punctuation mark removal, lemmatization, correction of common misspelled words, and reduction of replicated characters. We hypothesize that the application of different combinations of preprocessing methods can improve TC results. Therefore, we performed an extensive and systematic set of TC experiments (and this is our main research contribution) to explore the impact of all possible combinations of five/six basic preprocessing methods on four benchmark text corpora (and not samples of them) using three ML methods and training and test sets. The general conclusion (at least for the datasets verified) is that it is always advisable to perform an extensive and systematic variety of preprocessing methods combined with TC experiments because it contributes to improve TC accuracy. For all the tested datasets, there was always at least one combination of basic preprocessing methods that could be recommended to significantly improve the TC using a BOW representation. For three datasets, stopword removal was the only single preprocessing method that enabled a significant improvement compared to the baseline result using a bag of 1,000-word unigrams. For some of the datasets, there was minimal improvement when we removed HTML tags, performed spelling correction or removed punctuation marks, and reduced replicated characters. However, for the fourth dataset, the stopword removal was not beneficial. Instead, the conversion of uppercase letters into lowercase letters was the only single preprocessing method that demonstrated a significant improvement compared to the baseline result. The best result for this dataset was obtained when we performed spelling correction and conversion into lowercase letters. In general, for all the datasets processed, there was always at least one combination of basic preprocessing methods that could be recommended to improve the accuracy results when using a bag-of-words representation.

Dataset Information

Advancing bag-of-visual-words representations for lesion classification in retinal images.

Publications

Advancing bag-of-visual-words representations for lesion classification in retinal images.

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