Ontology highlight
ABSTRACT:
SUBMITTER: Ahtiainen K
PROVIDER: S-EPMC4043160 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Ahtiainen Katja K Mauno Jari J Ellä Ville V Hagström Jaana J Lindqvist Christian C Miettinen Susanna S Ylikomi Timo T Kellomäki Minna M Seppänen Riitta R
Journal of the Royal Society, Interface 20130529 85
The temporomandibular joint (TMJ) disc lacks functional replacement after discectomy. We investigated tissue-engineered bilayer polylactide (PLA) discs and autologous adipose stem cells (ASCs) as a potential replacement for the TMJ disc. These ASC discs were pre-cultured either in control or in differentiation medium, including transforming growth factor (TGF)-β1 for one week. Prior to implantation, expression of fibrocartilaginous genes was measured by qRT-PCR. The control and differentiated AS ...[more]