Ontology highlight
ABSTRACT:
SUBMITTER: Nagy JI
PROVIDER: S-EPMC4043341 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Nagy James Imre JI Urena-Ramirez Viridiana V Ghia Jean-Eric JE
FEBS letters 20140215 8
Neurons in the enteric nervous system utilize numerous neurotransmitters to orchestrate rhythmic gut smooth muscle contractions. We examined whether electrical synapses formed by gap junctions containing connexin36 also contribute to communication between enteric neurons in mouse colon. Spontaneous contractility properties and responses to electrical field stimulation and cholinergic agonist were altered in gut from connexin36 knockout vs. wild-type mice. Immunofluorescence revealed punctate lab ...[more]