Ontology highlight
ABSTRACT:
SUBMITTER: Airola MV
PROVIDER: S-EPMC4043343 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Airola Michael V MV Hannun Yusuf A YA
Handbook of experimental pharmacology 20130101 215
Sphingolipids are an important class of lipid molecules that play fundamental roles in our cells and body. Beyond a structural role, it is now clearly established that sphingolipids serve as bioactive signaling molecules to regulate diverse processes including inflammatory signaling, cell death, proliferation, and pain sensing. Sphingolipid metabolites have been implicated in the onset and progression of various diseases including cancer, lung disease, diabetes, and lysosomal storage disorders. ...[more]