Ontology highlight
ABSTRACT:
SUBMITTER: Finn EH
PROVIDER: S-EPMC4045483 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Finn Elizabeth H EH Smith Cheryl L CL Rodriguez Jesse J Sidow Arend A Baker Julie C JC
Developmental biology 20140302 1
To investigate the epigenetic landscape at the interface between mother and fetus, we provide a comprehensive analysis of parent-of-origin bias in the mouse placenta. Using F1 interspecies hybrids between mus musculus (C57BL/6J) and mus musculus castaneus, we sequenced RNA from 23 individual midgestation placentas, five late stage placentas, and two yolk sac samples and then used SNPs to determine whether transcripts were preferentially generated from the maternal or paternal allele. In the plac ...[more]