Ontology highlight
ABSTRACT:
SUBMITTER: Samy KP
PROVIDER: S-EPMC4047130 | biostudies-literature | 2014 May-Jun
REPOSITORIES: biostudies-literature
Samy Kannan P KP Martin Benjamin M BM Turgeon Nicole A NA Kirk Allan D AD
Xenotransplantation 20140508 3
Type I diabetes remains a significant clinical problem in need of a reliable, generally applicable solution. Both whole organ pancreas and islet allotransplantation have been shown to grant patients insulin independence, but organ availability has restricted these procedures to an exceptionally small subset of the diabetic population. Porcine islet xenotransplantation has been pursued as a potential means of overcoming the limits of allotransplantation, and several preclinical studies have achie ...[more]