Ontology highlight
ABSTRACT:
SUBMITTER: Liu D
PROVIDER: S-EPMC4048240 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Liu Dongyuan D Ma Chouxian C Hong Weiguo W Huang Long L Liu Min M Liu Hui H Zeng Huaping H Deng Dejing D Xin Huaigen H Song Jun J Xu Chunhua C Sun Xiaowen X Hou Xilin X Wang Xiaowu X Zheng Hongkun H
PloS one 20140606 6
Linkage maps enable the study of important biological questions. The construction of high-density linkage maps appears more feasible since the advent of next-generation sequencing (NGS), which eases SNP discovery and high-throughput genotyping of large population. However, the marker number explosion and genotyping errors from NGS data challenge the computational efficiency and linkage map quality of linkage study methods. Here we report the HighMap method for constructing high-density linkage m ...[more]