Ontology highlight
ABSTRACT:
SUBMITTER: Johnson DC
PROVIDER: S-EPMC4048334 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Johnson Derek C DC Shrestha Sadeep S Wiener Howard W HW Makowsky Robert R Kurundkar Ashish A Wilson Craig M CM Aissani Brahim B
Mitochondrial DNA 20131009 3
Genetic polymorphism along mitochondrial DNA (mtDNA) defines population-specific signatures called mtDNA haplogroups. Estimation of mtDNA haplogroup distribution may be prone to errors, notably if the study sample is not drawn from a multicenter cohort. Here, we report on mtDNA diversity in a sample of African American individuals (nā=ā343) enrolled in a multicenter cohort. Sequencing of the hypervariable regions I and II of the D-loop control region showed that the most common mitochondrial var ...[more]