Ontology highlight
ABSTRACT:
SUBMITTER: Wiemuth D
PROVIDER: S-EPMC4048340 | biostudies-literature | 2014 Jan-Feb
REPOSITORIES: biostudies-literature
Wiemuth Dominik D Assmann Marc M Gründer Stefan S
Channels (Austin, Tex.) 20131223 1
The DEG/ENaC gene family of ion channels is characterized by a high degree of structural similarity and an equally high degree of diversity concerning the physiological function. In humans and rodents, the DEG/ENaC family comprises 2 main subgroups: the subunits of the epithelial Na(+) channel (ENaC) and the subunits of the acid sensing ion channels (ASICs). The bile acid-sensitive channel (BASIC), previously known as BLINaC or INaC, represents a third subgroup within the DEG/ENaC family. Althou ...[more]