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Molecular catch and release: controlled delivery using optical trapping with light-responsive liposomes.


ABSTRACT: Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.

SUBMITTER: Leung SJ 

PROVIDER: S-EPMC4048806 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Molecular catch and release: controlled delivery using optical trapping with light-responsive liposomes.

Leung Sarah J SJ   Romanowski Marek M  

Advanced materials (Deerfield Beach, Fla.) 20120918 47


Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment. ...[more]

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