Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation.
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ABSTRACT:
SUBMITTER: Karlyshev AV
PROVIDER: S-EPMC4050187 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
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Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation.
Karlyshev A V AV Thacker G G Jones M A MA Clements M O MO Wren B W BW
FEBS open bio 20140509
According to MEROPS peptidase database, Campylobacter species encode 64 predicted peptidases. However, proteolytic properties of only a few of these proteins have been confirmed experimentally. In this study we identified and characterised a Campylobacter jejuni gene cj0511 encoding a novel peptidase. The proteolytic activity associated with this enzyme was demonstrated in cell lysates. Moreover, enzymatic studies conducted with a purified protein confirmed a prediction of it being a serine pept ...[more]
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