Ontology highlight
ABSTRACT:
SUBMITTER: Fassbinder-Orth CA
PROVIDER: S-EPMC4050711 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Fassbinder-Orth Carol A CA Barak Virginia A VA Rainwater Ellecia L EL Altrichter Ashley M AM
Vector borne and zoonotic diseases (Larchmont, N.Y.) 20140527 6
Birds serve as reservoirs for at least 10 arthropod-borne viruses, yet specific immune responses of birds to arboviral infections are relatively unknown. Here, adult House Sparrows were inoculated with an arboviral alphavirus, Buggy Creek virus (BCRV), or saline, and euthanized between 1 and 3 days postinoculation. Virological dynamics and gene expression dynamics were investigated. Birds did not develop viremia postinoculation, but cytopathic virus was found in the skeletal muscle and spleen of ...[more]