Ontology highlight
ABSTRACT:
SUBMITTER: McLean KC
PROVIDER: S-EPMC4051404 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
McLean Kelley C KC Oppenheimer Karen H KH Sweet Leigh M LM Phillippe Mark M
Reproductive sciences (Thousand Oaks, Calif.) 20120517 11
Phospholipid scramblases (PLSCR), stimulated by proinflammatory cytokines, are thought to mediate the loss of lipid asymmetry in cell membranes, allowing for specific reactions in the coagulation cascade. The PLSCR may therefore provide a link between inflammation, coagulation, and, because thrombin is a uterotonic, preterm birth (PTB). To explore the relationship between PLSCR expression and inflammation-related PTB, we utilized reverse transcriptase-polymerase chain reaction and Western blot s ...[more]