Ontology highlight
ABSTRACT:
SUBMITTER: Zou Z
PROVIDER: S-EPMC4052685 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
BioMed research international 20140513
Alzheimer's disease (AD) is the most common progressive neurodegenerative disease and the most common form of dementia in the elderly. It is a complex disorder with environmental and genetic components. There are two major types of AD, early onset and the more common late onset. The genetics of early-onset AD are largely understood with mutations in three different genes leading to the disease. In contrast, while susceptibility loci and alleles associated with late-onset AD have been identified ...[more]