Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC4052713 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Scientific reports 20140611
Preeclampsia (PE) is an excessive systemic inflammation response with dysfunction of endothelial. Our study was to investigate the association between genetic variations in IL-1 and the susceptibility to PE in Chinese Han population. 402 PE patients and 554 normal pregnant women of third trimester were enrolled. The polymorphisms of rs315952 in IL1RN and rs17561 in IL1A were genotyped by TaqMan allelic discrimination real-time PCR. Obviously statistic difference of the genotypic frequencies were ...[more]