CHANCE: comprehensive software for quality control and validation of ChIP-seq data.
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ABSTRACT:
SUBMITTER: Diaz A
PROVIDER: S-EPMC4053734 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
CHANCE: comprehensive software for quality control and validation of ChIP-seq data.
Diaz Aaron A Nellore Abhinav A Song Jun S JS
Genome biology 20121015 10
ChIP-seq is a powerful method for obtaining genome-wide maps of protein-DNA interactions and epigenetic modifications. CHANCE (CHip-seq ANalytics and Confidence Estimation) is a standalone package for ChIP-seq quality control and protocol optimization. Our user-friendly graphical software quickly estimates the strength and quality of immunoprecipitations, identifies biases, compares the user's data with ENCODE's large collection of published datasets, performs multi-sample normalization, checks ...[more]
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