Integrons: past, present, and future.
Ontology highlight
ABSTRACT:
SUBMITTER: Gillings MR
PROVIDER: S-EPMC4054258 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Integrons: past, present, and future.
Microbiology and molecular biology reviews : MMBR 20140601 2
Integrons are versatile gene acquisition systems commonly found in bacterial genomes. They are ancient elements that are a hot spot for genomic complexity, generating phenotypic diversity and shaping adaptive responses. In recent times, they have had a major role in the acquisition, expression, and dissemination of antibiotic resistance genes. Assessing the ongoing threats posed by integrons requires an understanding of their origins and evolutionary history. This review examines the functions a ...[more]
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