Ontology highlight
ABSTRACT:
SUBMITTER: Bastianelli D
PROVIDER: S-EPMC4054710 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Bastianelli Daniela D Siciliano Camilla C Puca Rosa R Coccia Andrea A Murdoch Colin C Bordin Antonella A Mangino Giorgio G Pompilio Giulio G Calogero Antonella A De Falco Elena E
BioMed research international 20140522
Mesenchymal stem cells (MSCs) represent a promising cell population for cell therapy and regenerative medicine applications. However, how variations in glucose are perceived by MSC pool is still unclear. Since, glucose metabolism is cell type and tissue dependent, this must be considered when MSCs are derived from alternative sources such as the heart. The zinc finger transcription factor Egr-1 is an important early response gene, likely to play a key role in the glucose-induced response. Our ai ...[more]