Functional annotation of proteome encoded by human chromosome 22.
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ABSTRACT:
SUBMITTER: Pinto SM
PROVIDER: S-EPMC4059257 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Functional annotation of proteome encoded by human chromosome 22.
Pinto Sneha M SM Manda Srikanth S SS Kim Min-Sik MS Taylor KyOnese K Selvan Lakshmi Dhevi Nagarajha LD Balakrishnan Lavanya L Subbannayya Tejaswini T Yan Fangfei F Prasad T S Keshava TS Gowda Harsha H Lee Charles C Hancock William S WS Pandey Akhilesh A
Journal of proteome research 20140429 6
As part of the chromosome-centric human proteome project (C-HPP) initiative, we report our progress on the annotation of chromosome 22. Chromosome 22, spanning 51 million base pairs, was the first chromosome to be sequenced. Gene dosage alterations on this chromosome have been shown to be associated with a number of congenital anomalies. In addition, several rare but aggressive tumors have been associated with this chromosome. A number of important gene families including immunoglobulin lambda l ...[more]
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