Ontology highlight
ABSTRACT:
SUBMITTER: Miyashita H
PROVIDER: S-EPMC4061549 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Miyashita Hiroaki H Chikazawa Miho M Otaki Natsuki N Hioki Yusuke Y Shimozu Yuki Y Nakashima Fumie F Shibata Takahiro T Hagihara Yoshihisa Y Maruyama Shoichi S Matsumi Noriyoshi N Uchida Koji K
Scientific reports 20140618
Covalent modification of proteins exerts significant effects on their chemical properties and has important functional and regulatory consequences. We now report the identification and verification of an electrically-active form of modified proteins recognized by a group of small molecules commonly used to interact with DNA. This previously unreported property of proteins was initially discovered when the γ-ketoaldehydes were identified as a source of the proteins stained by the DNA intercalator ...[more]