Ontology highlight
ABSTRACT:
SUBMITTER: Woodcock SR
PROVIDER: S-EPMC4061743 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Woodcock Steven R SR Salvatore Sonia R SR Bonacci Gustavo G Schopfer Francisco J FJ Freeman Bruce A BA
The Journal of organic chemistry 20131219 1
Nitro-conjugated linoleic acids (NO2-cLA), endogenous nitrodiene lipids which act as inflammatory signaling mediators, were isolated and single isomers purified from the biomimetic acidic nitration products of conjugated linoleic acid (CLA). Structures were elucidated by means of detailed NMR and HPLC-MS/MS spectroscopic analysis and the relative double bond configurations assigned. Additional synthetic methods produced useful quantities and similar isomeric distributions of these unusual and re ...[more]