Ontology highlight
ABSTRACT:
SUBMITTER: Laydon DJ
PROVIDER: S-EPMC4063693 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Laydon Daniel J DJ Melamed Anat A Sim Aaron A Gillet Nicolas A NA Sim Kathleen K Darko Sam S Kroll J Simon JS Douek Daniel C DC Price David A DA Bangham Charles R M CR Asquith Becca B
PLoS computational biology 20140619 6
Estimation of immunological and microbiological diversity is vital to our understanding of infection and the immune response. For instance, what is the diversity of the T cell repertoire? These questions are partially addressed by high-throughput sequencing techniques that enable identification of immunological and microbiological "species" in a sample. Estimators of the number of unseen species are needed to estimate population diversity from sample diversity. Here we test five widely used non- ...[more]