A novel cell death gene acts to repair patterning defects in Drosophila melanogaster.
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ABSTRACT:
SUBMITTER: Tanaka KM
PROVIDER: S-EPMC4063928 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
A novel cell death gene acts to repair patterning defects in Drosophila melanogaster.
Tanaka Kentaro M KM Takahashi Aya A Fuse Naoyuki N Takano-Shimizu-Kouno Toshiyuki T
Genetics 20140325 2
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development. ...[more]
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