Impact of genomics on the field of probiotic research: historical perspectives to modern paradigms.
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ABSTRACT:
SUBMITTER: Johnson BR
PROVIDER: S-EPMC4064118 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Publications
Impact of genomics on the field of probiotic research: historical perspectives to modern paradigms.
Johnson Brant R BR Klaenhammer Todd R TR
Antonie van Leeuwenhoek 20140420 1
For thousands of years, humans have safely consumed microorganisms through fermented foods. Many of these bacteria are considered probiotics, which act through diverse mechanisms to confer a health benefit to the host. However, it was not until the availability of whole-genome sequencing and the era of genomics that mechanisms of probiotic efficacy could be discovered. In this review, we explore the history of the probiotic concept and the current standard of integrated genomic techniques to dis ...[more]
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