Ontology highlight
ABSTRACT:
SUBMITTER: Farah BL
PROVIDER: S-EPMC4064960 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Farah Benjamin L BL Sinha Rohit A RA Wu Yajun Y Singh Brijesh K BK Zhou Jin J Bay Boon-Huat BH Yen Paul M PM
PloS one 20140620 6
Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function. However, currently little is known about the potential role of adrenergic signaling on hepatic autophagy, and whether the β-adrenergic receptor itself may be a key regulator of autophagy. To address these issues, we investigated the actions of the β2-adrenergic ...[more]