Ontology highlight
ABSTRACT:
SUBMITTER: Richardson MB
PROVIDER: S-EPMC4066366 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Richardson Mark B MB Williams Spencer J SJ
Frontiers in immunology 20140623
Macrophage C-type lectin (MCL) and macrophage inducible C-type lectin (Mincle) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage-associated and pathogen-associated molecular patterns. In this review, we cover the discovery and molecular characterization of these C-type lectin receptors, and highlight recent advances in the understanding of their roles in orchestrating the response of the immune system to bacterial and fungal infection, and ...[more]