Ontology highlight
ABSTRACT:
SUBMITTER: Trenchevska O
PROVIDER: S-EPMC4067327 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Trenchevska Olgica O Phillips David A DA Nelson Randall W RW Nedelkov Dobrin D
PloS one 20140623 6
Human protein diversity arises as a result of alternative splicing, single nucleotide polymorphisms (SNPs) and posttranslational modifications. Because of these processes, each protein can exists as multiple variants in vivo. Tailored strategies are needed to study these protein variants and understand their role in health and disease. In this work we utilized quantitative mass spectrometric immunoassays to determine the protein variants concentration of beta-2-microglobulin, cystatin C, retinol ...[more]