Ontology highlight
ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC4068549 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Chen Liang L Chavda Kalyan D KD Findlay Jacqueline J Peirano Gisele G Hopkins Katie K Pitout Johann D D JD Bonomo Robert A RA Woodford Neil N DeLeo Frank R FR Kreiswirth Barry N BN
Antimicrobial agents and chemotherapy 20140414 7
We developed a multiplex PCR assay capable of identifying two capsular polysaccharide synthesis sequence types (sequence type 258 [ST258] cps-1 and cps-2) in epidemic Klebsiella pneumoniae ST258 strains. The assay performed with excellent sensitivity (100%) and specificity (100%) for identifying cps types in 60 ST258 K. pneumoniae sequenced isolates. The screening of 419 ST258 clonal isolates revealed a significant association between cps type and K. pneumoniae carbapenemase (KPC) variant: cps-1 ...[more]