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Examining mediators of housing mobility on adolescent asthma: results from a housing voucher experiment.

ABSTRACT: Literature on neighborhood effects on health largely employs non-experimental study designs and does not typically test specific neighborhood mediators that influence health. We address these gaps using the Moving to Opportunity (MTO) housing voucher experiment. Research has documented both beneficial and adverse effects on health in MTO, but mediating mechanisms have not been tested explicitly. We tested mediation of MTO effects on youth asthma (n = 2829). MTO randomized families living in public housing to an experimental group receiving a voucher to subsidize rental housing, or a control group receiving no voucher, and measured outcomes 4-7 years following randomization. MTO had a harmful main effect vs. controls for self-reported asthma diagnosis (b = 0.24, p = 0.06), past-year asthma attack (b = 0.44, p = 0.02), and past-year wheezing (b = 0.17, p = 0.17). Using Inverse Odds Weighting mediation we tested mental health, smoking, and four housing dimensions as potential mediators of the MTO-asthma relationship. We found no significant mediation overall, but mediation may be gender-specific. Gender-stratified models displayed countervailing mediation effects among girls for asthma diagnosis by smoking (p = 0.05) and adult-reported housing quality (p = 0.06), which reduced total effects by 35% and 42% respectively. MTO treatment worsened boys' mental health and mental health reduced treatment effects on asthma diagnosis by 27%. Future research should explore other potential mediators and gender-specific mediators of MTO effects on asthma. Improving measurement of housing conditions and other potential mediators may help elucidate the "black box" of neighborhood effects.

SUBMITTER: Schmidt NM

PROVIDER: S-EPMC4070421 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Examining mediators of housing mobility on adolescent asthma: results from a housing voucher experiment.

Schmidt Nicole M NM Lincoln Alisa K AK Nguyen Quynh C QC Acevedo-Garcia Dolores D Osypuk Theresa L TL

Social science & medicine (1982) 20140214

Literature on neighborhood effects on health largely employs non-experimental study designs and does not typically test specific neighborhood mediators that influence health. We address these gaps using the Moving to Opportunity (MTO) housing voucher experiment. Research has documented both beneficial and adverse effects on health in MTO, but mediating mechanisms have not been tested explicitly. We tested mediation of MTO effects on youth asthma (n = 2829). MTO randomized families living in publ ...[more]

PMID: 24607675

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Project description:AimsTo test how a housing voucher generating residential mobility to lower-poverty neighborhoods, compared with public housing controls, influenced adolescent binge drinking, and whether gender modified effects.DesignA multi-site household-level three-arm randomized trial of a housing intervention executed 1994-98, evaluated 2001-02.SettingFive US cities: Baltimore, MD; Boston, MA; Chicago, IL; Los Angeles, CA; and New York, NY.ParticipantsA total of 3537 adolescents in 4248 low-income eligible families were randomized; 2829 adolescents were analyzed at the interim evaluation (1950 in treatment; 879 in the control group). Attrition bias was accounted for with a 3-in-10 oversampling of hard-to-reach participants (effective response rate: 89%).InterventionsThe Moving to Opportunity (MTO) trial randomized volunteer low-income families in public housing to receive (1) rental subsidies redeemable in neighborhoods with < 10% tract poverty plus housing counseling, (2) unrestricted Section 8 rental subsidies or (3) to remain in public housing. We pooled the subsidy ('treatment') groups because they were conceptually similar and there was no evidence of statistical differences between groups on binge drinking.MeasurementsPrimary outcome: past month binge drinking (five or more drinks in one sitting).FindingsAdolescent binge drinking prevalence was 3.9% for treatment and 3.2% for control. The intention-to-treat (ITT) main effect of subsidy treatment (versus control) on binge drinking was non-significant, but treatment effects were different for girls and boys (treatment-gender interaction P = 0.002). MTO treatment reduced girls' binge drinking [odds ratio (OR) = 0.48, 95% confidence interval (CI) = 0.24-0.96, P = 0.037], but increased boys' binge drinking (OR = 2.37, 95% CI = 1.13-4.97, P = 0.023), compared with controls. Results were similar for secondary alcohol outcomes. Instrumental variable (IV) results adjusting for treatment compliance were comparable with ITT, but larger.ConclusionsA housing subsidy treatment that enables low-income families to move from public to private housing appears to lessen girls' binge drinking but increases boys' binge drinking, compared with controls.

Project description:ImportanceStructural racism has been implicated in the disproportionally high asthma morbidity experienced by children living in disadvantaged, urban neighborhoods. Current approaches designed to reduce asthma triggers have modest impact.ObjectiveTo examine whether participation in a housing mobility program that provided housing vouchers and assistance moving to low-poverty neighborhoods was associated with reduced asthma morbidity among children and to explore potential mediating factors.Design, setting, and participantsCohort study of 123 children aged 5 to 17 years with persistent asthma whose families participated in the Baltimore Regional Housing Partnership housing mobility program from 2016 to 2020. Children were matched to 115 children enrolled in the Urban Environment and Childhood Asthma (URECA) birth cohort using propensity scores.ExposureMoving to a low-poverty neighborhood.Main outcomesCaregiver-reported asthma exacerbations and symptoms.ResultsAmong 123 children enrolled in the program, median age was 8.4 years, 58 (47.2%) were female, and 120 (97.6%) were Black. Prior to moving, 89 of 110 children (81%) lived in a high-poverty census tract (>20% of families below the poverty line); after moving, only 1 of 106 children with after-move data (0.9%) lived in a high-poverty tract. Among this cohort, 15.1% (SD, 35.8) had at least 1 exacerbation per 3-month period prior to moving vs 8.5% (SD, 28.0) after moving, an adjusted difference of -6.8 percentage points (95% CI, -11.9% to -1.7%; P = .009). Maximum symptom days in the past 2 weeks were 5.1 (SD, 5.0) before moving and 2.7 (SD, 3.8) after moving, an adjusted difference of -2.37 days (95% CI, -3.14 to -1.59; P < .001). Results remained significant in propensity score-matched analyses with URECA data. Measures of stress, including social cohesion, neighborhood safety, and urban stress, all improved with moving and were estimated to mediate between 29% and 35% of the association between moving and asthma exacerbations.Conclusions and relevanceChildren with asthma whose families participated in a program that helped them move into low-poverty neighborhoods experienced significant improvements in asthma symptom days and exacerbations. This study adds to the limited evidence suggesting that programs to counter housing discrimination can reduce childhood asthma morbidity.

Project description:ImportanceAlthough neighborhoods are thought to be an important health determinant, evidence for the relationship between neighborhood poverty and health care use is limited, as prior studies have largely used observational data without an experimental design.ObjectiveTo examine whether housing policies that reduce exposure to high-poverty neighborhoods were associated with differences in long-term hospital use among adults and children.Design, setting, and participantsExploratory analysis of the Moving to Opportunity for Fair Housing Demonstration Program, a randomized social experiment conducted in 5 US cities. From 1994 to 1998, 4604 families in public housing were randomized to 1 of 3 groups: a control condition, a traditional Section 8 voucher toward rental costs in the private market, or a voucher that could only be used in low-poverty neighborhoods. Participants were linked to all-payer hospital discharge data (1995 through 2014 or 2015) and Medicaid data (1999 through 2009). The final follow-up date ranged from 11 to 21 years after randomization.ExposuresReceipt of a traditional or low-poverty voucher vs control group.Main outcomes and measuresRates of hospitalizations and hospital days, and hospital spending.ResultsAmong 4602 eligible individuals randomized as adults, 4072 (88.5%) were linked to health data (mean age, 33 years [SD, 9.0 years]; 98% female; median follow-up, 11 years). There were no significant differences in primary outcomes among adults randomized to receive a voucher compared with the control group (unadjusted hospitalization rate, 14.0 vs 14.7 per 100 person-years, adjusted incidence rate ratio [IRR], 0.95 [95% CI, 0.84-1.08; P?=?.45]; hospital days, 62.8 vs 67.0 per 100 person-years; IRR, 0.93 [95% CI, 0.77-1.13; P?=?.46]; yearly spending, $2075 vs $1977; adjusted difference, -$129 [95% CI, -$497 to $239; P?=?.49]). Among 11?290 eligible individuals randomized as children, 9118 (80.8%) were linked to health data (mean age, 8 years [SD, 4.6 years]; 49% female; median follow-up, 11 years). Receipt of a housing voucher during childhood was significantly associated with lower hospitalization rates (6.3 vs 7.3 per 100 person-years; IRR, 0.85 [95% CI, 0.73-0.99; P?=?.03]) and yearly inpatient spending ($633 vs $785; adjusted difference, -$143 [95% CI, -$256 to -$31; P?=?.01]) and no significant difference in hospital days (25.7 vs 28.8 per 100 person-years; IRR, 0.92 [95% CI, 0.77-1.11; P?=?.41]).Conclusions and relevanceIn this exploratory analysis of a randomized housing voucher intervention, adults who received a housing voucher did not experience significant differences in hospital use or spending. Receipt of a voucher during childhood was significantly associated with lower rates of hospitalization and less inpatient spending during long-term follow-up.

Dataset Information

Examining mediators of housing mobility on adolescent asthma: results from a housing voucher experiment.

Publications

Examining mediators of housing mobility on adolescent asthma: results from a housing voucher experiment.

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