Ontology highlight
ABSTRACT:
SUBMITTER: Hung TC
PROVIDER: S-EPMC4071968 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
BioMed research international 20140611
Human immunodeficiency virus causes the acquired immunodeficiency syndrome (AIDS) and becomes a serious world-wide problem because of this disease's rapid propagation and incurability. Integrase strand transfer inhibitors (INSTIs) supports HIV have rapid drug resistance for antitreatment. Screening the traditional Chinese medicine (TCM) database by simulating molecular docking and molecular dynamics may select molecular compounds to inhibit INSTIs against HIV drug resistance. (S)-cathinone and ( ...[more]