Ontology highlight
ABSTRACT:
SUBMITTER: Niewczas MA
PROVIDER: S-EPMC4072128 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Niewczas Monika A MA Sirich Tammy L TL Mathew Anna V AV Skupien Jan J Mohney Robert P RP Warram James H JH Smiles Adam A Huang Xiaoping X Walker Walker W Byun Jaeman J Karoly Edward D ED Kensicki Elizabeth M EM Berry Gerard T GT Bonventre Joseph V JV Pennathur Subramaniam S Meyer Timothy W TW Krolewski Andrzej S AS
Kidney international 20140115 5
Here we studied plasma metabolomic profiles as determinants of progression to end-stage renal disease (ESRD) in patients with type 2 diabetes (T2D). This nested case-control study evaluated 40 cases who progressed to ESRD during 8-12 years of follow-up and 40 controls who remained alive without ESRD from the Joslin Kidney Study cohort. Controls were matched with cases for baseline clinical characteristics, although controls had slightly higher eGFR and lower levels of urinary albumin excretion t ...[more]