Ontology highlight
ABSTRACT:
SUBMITTER: Moradigaravand D
PROVIDER: S-EPMC4072600 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
PLoS genetics 20140626 6
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory on the impact of recombination on the evolutionary dynamics of adapting populations, empirical evidence to test these theories is still scarce. We examined the effect of recombination on adaptation on a large-scale empirical fitness landscape in HIV-1 based on in vitro fitness measurements. Our results indicate that recombination substantially increases the rate of adaptation under a wide range o ...[more]