Ontology highlight
ABSTRACT:
SUBMITTER: Dai J
PROVIDER: S-EPMC4072910 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Dai Jingyao J Gu Jian J Huang Maosheng M Eng Cathy C Kopetz E Scott ES Ellis Lee M LM Hawk Ernest E Wu Xifeng X
Carcinogenesis 20120412 7
Recent genome-wide association studies (GWAS) have identified several common susceptibility loci associated with the risk of colorectal cancer (CRC). However, whether these loci affect clinical outcomes of CRC is not clear. In this study, we genotyped 26 single nucleotide polymorphisms (SNPs) in 10 GWAS-identified CRC susceptibility regions and evaluated their associations with survival and recurrence in 285 stage II and III patients receiving fluorouracil-based adjuvant chemotherapy. Only one S ...[more]