Histone methylation: a dynamic mark in health, disease and inheritance.
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ABSTRACT:
SUBMITTER: Greer EL
PROVIDER: S-EPMC4073795 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Publications
Histone methylation: a dynamic mark in health, disease and inheritance.
Nature reviews. Genetics 20120403 5
Organisms require an appropriate balance of stability and reversibility in gene expression programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation is integral to this dynamic control. Post-translational modification of histones by methylation is an important and widespread type of chromatin modification that is known to influence biological processes in the context of development and cellular responses. To evaluate how histone methylation contributes to stab ...[more]
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