Dataset Information

Early public response to influenza A(H7N9) virus, Guangzhou, China, May 30-June 7, 2013.

ABSTRACT:

SUBMITTER: Yuan J

PROVIDER: S-EPMC4073867 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Early public response to influenza A(H7N9) virus, Guangzhou, China, May 30-June 7, 2013.

Yuan Jun J Liao Qiuyan Q Lau Eric H Y EH Yang Zhi Cong ZC Wei Xiao X Chen Jian Dong JD Liu Yan Hui YH Wang Chang C Tang Xiao Ping XP Liu Yu Fei YF Leung Gabriel M GM Xiao Xin Cai XC Fielding Richard R Wang Ming M Cowling Benjamin J BJ

Emerging infectious diseases 20140701 7

PMID: 24964006

Similar Datasets

Project description:PurposeA virologic surveillance program for A(H7N9) virus was conducted from April 15, 2013 to February 14, 2014 in Guangzhou, aiming to clarify the geographical distribution of A(H7N9) viruses among live poultry markets (LPMs) and poultry farms in Guangzhou. Virological and serological surveys of poultry workers were also conducted to evaluate the risk of poultry-to-human transmission of the A(H7N9) virus.Methods36 retail LPMs, 6 wholesale LPMs and 8 poultry farms were involved in our surveillance program. About 20 live poultry and environmental samples were obtained from each surveillance site at every sampling time. Different environmental samples were collected to represent different poultry-related work activities. RT-PCR and virus culture were performed to identify the A(H7N9) virus. Hemagglutinin inhibition assay and RT-PCR were conducted to detect possible A(H7N9) infection among poultry workers.ResultsA total of 8900 live poultry and environmental samples were collected, of which 131(1.5%) were tested positive for A(H7N9) virus. 44.4% (16/36) of retail LPMs and 50.0% (3/6) of wholesale LPMs were confirmed to be contaminated. No positive samples was detected from poultry farms. A significant higher positive sample rate was found in environmental samples related to poultry selling (2.6%) and slaughtering (2.4%), compared to poultry holding (0.9%). Correspondingly, A(H7N9) viruses were isolated most frequently from slaughter zone. In addition, 316 poultry workers associated with the 19 contaminated-LPMs were recruited and a low seroprevalence (1.6%) of antibody against A(H7N9) virus was detected. An asymptomatic A(H7N9) infection was also identified by RT-PCR.ConclusionsOur study highlights the importance of conducting effective surveillance for A(H7N9) virus and provides evidence to support the assumption that slaughtering is the key process for the propagation of A(H7N9) virus in retail LPMs. Moreover, the ability of A(H7N9) virus to cross species barrier is proved to be still limited.

Dataset Information

Early public response to influenza A(H7N9) virus, Guangzhou, China, May 30-June 7, 2013.

Publications

Early public response to influenza A(H7N9) virus, Guangzhou, China, May 30-June 7, 2013.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets