Ontology highlight
ABSTRACT:
SUBMITTER: Abid SN
PROVIDER: S-EPMC4076406 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Abid Shadaan N SN Richardson Timothy E TE Powell Heather M HM Jaichander Priscilla P Chaudhary Jaideep J Chapman Karen M KM Hamra F Kent FK
Biology of reproduction 20140213 2
In mammalian testes, "A-single" spermatogonia function as stem cells that sustain sperm production for fertilizing eggs. Yet, it is not understood how cellular niches regulate the developmental fate of A-single spermatogonia. Here, immunolabeling studies in rat testes define a novel population of ERBB3(+) germ cells as approximately 5% of total SNAP91(+) A-single spermatogonia along a spermatogenic wave. As a function of time, ERBB3(+) A-single spermatogonia are detected during a 1- to 2-day per ...[more]