Ontology highlight
ABSTRACT:
SUBMITTER: Ravichandiran P
PROVIDER: S-EPMC4076656 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Journal of chemical biology 20140612 3
A new series of new 1,4-naphthoquinone derivatives containing carbazole-6,11-dione moiety, which has not been reported yet, has been synthesized from 1,4-naphthoquinone and 4-aminophenylsulfone involving a Michael addition, benzoylation, and Pd-catalyzed coupling. This set of compounds has been evaluated for in vitro antibacterial studies against different Gram-positive and Gram-negative bacteria, and most of the synthesized compounds exhibited good antibacterial activity and the minimum inhibit ...[more]