Dataset Information

Development and validation of a rapid, generic measure of disease control from the patient's perspective: the IBD-control questionnaire.

ABSTRACT:

Introduction

The use of patient reported outcome measures to support routine inflammatory bowel disease (IBD) care is not widespread and suggests that existing questionnaires lack relevance to day-to-day decisions or are too cumbersome to administer. We developed a simple, generic tool for capturing disease control from the patient's perspective to address these barriers.

Methods

Development based on literature review, patient focus groups/interviews and a steering group, defining a limited set of generic questions. The 'IBD-Control' questionnaire comprises 13 items plus a visual analogue scale (VAS) (0-100). Prospective validation involved baseline completion of IBD-Control, quality of life (QoL) questionnaire (UK-IBD-Q), EuroQol (EQ-5D), Hospital Anxiety and Depression Score; and clinician assessment (blinded to questionnaire; recording Harvey-Bradshaw Index or Simple Clinical Colitis Activity Index; Global Clinician Rating; treatment outcome).

Results

299 patients returned baseline surveys (Crohn's disease, n=160; ulcerative colitis, n=139) and 138 attended for repeat visits. Completion time (mean; SD): 1?min 15?s; 25?s; Internal consistency: Cronbach's ? for all 13 items (0.85); for subgroup of eight questions ('IBD-Control-8'; 0.86). Strong correlation between IBD-Control-8 and IBD-Control-VAS (r=0.81). Test-retest reliability (2?week repeat): intra-class correlation=0.97 for IBD-Control-8 and 0.96 for IBD-Control-VAS. Construct validity: Moderate-to-strong correlations between IBD-Control-8 and IBD-Control-VAS versus activity indices, UK-IBD-Q and EQ-5D (utility) with r values 0.52-0.86. Discriminant validity (mean instrument scores for remission, mild, moderate or severe): p<0.001 (analysis of variance (ANOVA)). Sensitivity to change: Effect sizes: 0.76-1.44.

Conclusions

The IBD-Control is a rapid, reliable, valid and sensitive instrument for measuring overall disease control from the patient's perspective. Unlike existing patient reported outcome measures, its simplicity, ease-of-use and generic applicability make it a candidate for supporting routine care.

SUBMITTER: Bodger K

PROVIDER: S-EPMC4078750 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Publications

Development and validation of a rapid, generic measure of disease control from the patient's perspective: the IBD-control questionnaire.

Bodger Keith K Ormerod Clare C Shackcloth Daniela D Harrison Melanie M

Gut 20131009 7

<h4>Introduction</h4>The use of patient reported outcome measures to support routine inflammatory bowel disease (IBD) care is not widespread and suggests that existing questionnaires lack relevance to day-to-day decisions or are too cumbersome to administer. We developed a simple, generic tool for capturing disease control from the patient's perspective to address these barriers.<h4>Methods</h4>Development based on literature review, patient focus groups/interviews and a steering group, defining ...[more]

PMID: 24107590

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Dataset Information

Development and validation of a rapid, generic measure of disease control from the patient's perspective: the IBD-control questionnaire.

Introduction

Methods

Results

Conclusions

Publications

Development and validation of a rapid, generic measure of disease control from the patient's perspective: the IBD-control questionnaire.

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