Ontology highlight
ABSTRACT:
SUBMITTER: Ma J
PROVIDER: S-EPMC4078997 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Nature communications 20140520
The intestinal microbiome is a unique ecosystem and an essential mediator of metabolism and obesity in mammals. However, studies investigating the impact of the diet on the establishment of the gut microbiome early in life are generally lacking, and most notably so in primate models. Here we report that a high-fat maternal or postnatal diet, but not obesity per se, structures the offspring's intestinal microbiome in Macaca fuscata (Japanese macaque). The resultant microbial dysbiosis is only par ...[more]