The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in idiopathic trigeminal neuralgia patients.
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ABSTRACT:
SUBMITTER: Cui W
PROVIDER: S-EPMC4080683 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in idiopathic trigeminal neuralgia patients.
Cui Wenyao W Yu Xue X Zhang Huiqian H
The journal of headache and pain 20140620
<h4>Background</h4>To investigate the possible association between the serotonin transporter gene (5-HTTLPR) and rs 25531 polymorphism and the susceptibility and the pain severity in Trigeminal Neuralgia patients.<h4>Methods</h4>A total of 244 TN patients and 280 age and sex matched healthy volunteer were recruited. 5-HTTLPR and rs 25531 genotyping were performed. All patients received the carbamazepine treatment and the treatment response was evaluated at 6 months.<h4>Results</h4>The genotype d ...[more]
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