Ontology highlight
ABSTRACT:
SUBMITTER: Cotlarciuc I
PROVIDER: S-EPMC4083192 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Cotlarciuc Ioana I Malik Rainer R Holliday Elizabeth G EG Ahmadi Kourosh R KR Paré Guillaume G Psaty Bruce M BM Fornage Myriam M Hasan Nazeeha N Rinne Paul E PE Ikram M Arfan MA Markus Hugh S HS Rosand Jonathan J Mitchell Braxton D BD Kittner Steven J SJ Meschia James F JF van Meurs Joyce B J JB Uitterlinden Andre G AG Worrall Bradford B BB Dichgans Martin M Sharma Pankaj P
Stroke 20140520 7
<h4>Background and purpose</h4>Elevated total plasma homocysteine (tHcy) levels are known to be associated with increased risk of ischemic stroke (IS). Given that both tHcy and IS are heritable traits, we investigated a potential genetic relationship between homocysteine levels and stroke risk by assessing 18 polymorphisms previously associated with tHcy levels for their association with IS and its subtypes.<h4>Methods</h4>Previous meta-analysis results from an international stroke collaborative ...[more]