Ontology highlight
ABSTRACT:
SUBMITTER: Klockner A
PROVIDER: S-EPMC4083426 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Klöckner Anna A Otten Christian C Derouaux Adeline A Vollmer Waldemar W Bühl Henrike H De Benedetti Stefania S Münch Daniela D Josten Michaele M Mölleken Katja K Sahl Hans-Georg HG Henrichfreise Beate B
Nature communications 20140623
Intracellular Chlamydiaceae do not need to resist osmotic challenges and a functional cell wall was not detected in these pathogens. Nevertheless, a recent study revealed evidence for circular peptidoglycan-like structures in Chlamydiaceae and penicillin inhibits cytokinesis, a phenomenon known as the chlamydial anomaly. Here, by characterizing a cell wall precursor-processing enzyme, we provide insights into the mechanisms underlying this mystery. We show that AmiA from Chlamydia pneumoniae sep ...[more]