Ontology highlight
ABSTRACT:
SUBMITTER: Berry JA
PROVIDER: S-EPMC4083655 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Neuron 20120501 3
Psychological studies in humans and behavioral studies of model organisms suggest that forgetting is a common and biologically regulated process, but the molecular, cellular, and circuit mechanisms underlying forgetting are poorly understood. Here we show that the bidirectional modulation of a small subset of dopamine neurons (DANs) after olfactory learning regulates the rate of forgetting of both punishing (aversive) and rewarding (appetitive) memories. Two of these DANs, MP1 and MV1, exhibit s ...[more]