Ontology highlight
ABSTRACT:
SUBMITTER: Gromowski GD
PROVIDER: S-EPMC4083695 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Gromowski Gregory D GD Firestone Cai-Yen CY Hanson Christopher T CT Whitehead Stephen S SS
Vaccine 20140331 25
Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis worldwide and vaccination is one of the most effective ways to prevent disease. A suitable live-attenuated JEV vaccine could be formulated with a live-attenuated tetravalent dengue vaccine for the control of these viruses in endemic areas. Toward this goal, we generated chimeric virus vaccine candidates by replacing the precursor membrane (prM) and envelope (E) protein structural genes of recombinant dengue virus type 4 ( ...[more]